: p Specifications : 2 Pages , 3 Sources , CBE Style: language forge the Addison unsoundness , and pheochromocytoma . How it raises in the human dead physical structureAddison s disease or ` adrenal gland want is a determine in which the adrenal glands do not lay knock off sufficient amounts of the endocrine hydrocortisone (Mayo 2006 . This hormone helps to control the root pressure cardiovascular action mechanism , resistive responses , insulin occasion , metabolism etc in the body (NIDDK 2004 . In some cases , a hormone that controls the blood pressure and the changeable balance in the body (aldosterone ) is as well take uped (NIDDK 2004 . The adrenal glands argon position above the kidneys and produce several another(prenominal) hormones required for normal mathematical process of the body (Mayo 2006 . Ad dison s disease fire occur in some(prenominal) sexes equ ally and in all age sepa aims , but is more(prenominal) common in the middle-age group (Mayo 2006 . The hypophysis gland and the hypothalamus (structures insert in the skull ) control the activeness of the adrenal gland by ensuring proper yield and come forth of the hydrocortisone hormone The hypothalamus produces a hormone CRH (corticotropin-releasing hormone , that stimulates the hypophysis to produce the adrenocorticotrophic hormone hormones that further stimulates the adrenal glands to release hydrocortisone (NIDDK 2004 . Addison s disease whitethorn develop ascribable to inadequate end product of cortisol by the adrenal gland ( first-string inadequateness ) or ascribable to decreased stimulation from the hypophysis gland (secondary insufficiency (NIDDK 2004 . native adrenal insufficiency may develop imputable to an immune dysfunction . Most of the cases of develop due to the body s justification mechanism attacking the tissues of the adre! nal cortex and resulting in deficient production of the hormone (NIDDK 2004 . Primary adrenal insufficiency may also develop in association with `Polyendocrine inadequacy Syndrome , in which several hormonal directs are deficient due to a genetic dis (NIDDK 2004 . Several other causes including tuberculosis , infections , phlebotomize , tumors , rotate of tumors , surgery , etc , of the adrenal glands could result in primary insufficiency (Mayo 2006 .
Secondary adrenal insufficiency can develop due to reduced production of adrenocorticotropic hormone by the pituitary glands or CRH by the hypothalamus (Mayo 2006 . The ACTH production stimulates the adrenal glands to produce cortisol , and the CRH hormone encourages the pituitary to release ACTH (NIDDK 2004 . The level of ACTH is controlled by a negative feedback mechanism . Tumors that affect the pituitary , surgical removal of the gland , radiotherapy to the run and neck region , reduced supply of blood to the pituitary , etc , could also result in secondary adrenal insufficiency (NIDDK 2004pheochromocytoma is a tumor that arises from adrenal glands that result in profligate production of the hormones epinephrine and nor-epinephrine (Mayo 2006 . These hormones control the blood pressure , the rate at which the heart beats and several other activities in the body (Nanda 2006 . They are required especially in idiomful conditions such(prenominal) as fright , flight and fight , aflame stress , etc (Mayo 2006 . The tumor develops from the inner portion of the adrenal gland cognise as `adrenal medulla (Nanda 2006 . Most of the Pheochromocytoma are benign or self-limiting in nature...If you want to nec essitate a full essay, order it on our website: OrderEssay.net
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